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Evidence Service to support the COVID-19 response May 18, 2020 Meriel Raymond, Gemma Ching-A-Sue, Oliver Van Hecke On behalf of the Oxford COVID-19 Evidence Service Team Centre for Evidence-Based Medicine, Nuffield Department of Primary Care Health Sciences University of Oxford Correspondence to [email protected] VERDICT Mast cells are the main source of cytokine release that leads to lung damage in SARS-CoV-2

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In the case of multiple records pertaining to the same trial (i.e., original fulltext publication, abstract, and post hoc analyses), we collected all relevant data and analyzed them as a single study

While the research is promising, more human studies are needed